The work "Metal–Organic Frameworks in Surface-Enhanced Raman Spectroscopy–Based Analysis of Volatile Organic Compounds" by Dr. Juan Allegretto and Dr. Jakub Dostalek is now available Open Access in Advanced Science!
Volatile Organic Compounds (VOCs) are a major class of compounds with the duality of being pollutants hazardous to human health and relevant for applications such as early disease diagnostics and organoleptic perception (odor and taste). This review summarizes the world of VOC detection by means of Metal-Organic Frameworks (MOF)-based Surface-Enhanced Raman Spectroscopy (SERS) substrates. This unique combination of MOF and SERS provides a platform for rapid, sensitive, and accurate analysis of VOCs. Our review focuses on elucidating respective design rules for maximizing analytical performance. An overview of the status of the detection of harmful VOCs is discussed in the context of industrial and environmental monitoring. In addition, a survey of the analysis of VOC biomarkers for medical diagnosis and emerging applications in aroma and flavor profiling is included.
This work has been funded by the Austrian Science Fund – FWF through the project “Tailoring Plasmonics & MOFs: Synergy for Odorant Sensing,” which is deeply acknowledged.
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